NATRIUM-PENTOBARBITAL TIERMEDIZIN - AN OVERVIEW

pentobarbital will lower the level or impact of midostaurin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Strong CYP3A4 inducers may lessen midostaurin concentrations leading to decreased efficacy.pentobarbital will minimize the extent or impact of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism.